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HPU / KPU – testing & support in Berlin
With HPU (also called KPU or pyroluria), the body produces excess pyrroles. To excrete them, it binds them to zinc and vitamin B6 – a chronic shortage of these nutrients can be the result.
Certified HPU&YOU coach
Training with Sonja Schmitzer & Sonja Ilitz
Does this sound familiar?
Mental well-being
anxiety, low mood, stress
Physical vitality
fatigue, poor sleep
Cognitive function
brain fog, focus
Digestive health
gut issues, sensitivities
You don’t need to have every symptom when being HPU positive
What is HPU?
A metabolic peculiarity in which more pyrroles are produced. They bind zinc and vitamin B6 – both are needed for nerves, hormones and the immune system.
The test
HPU is determined with a urine sample that you can take comfortably at home and send to a specialist laboratory.
My support
As a certified HPU&YOU coach, I support you from testing to your individual therapy – with targeted nutrient supply and a view of gut, hormones and stress.
Frequently asked questions
What exactly is HPU / KPU?
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Haemopyrrollactamuria (HPU) and kryptopyrroluria (KPU) describe a genetically determined metabolic disorder in which the formation of the haem molecule (an important building block of the blood) does not proceed correctly. The resulting by-products bind to vital nutrients – above all activated vitamin B6 (P5P), zinc and manganese – and are increasingly excreted in the urine. In the long term, this can lead to a chronic micronutrient deficiency with a wide range of complaints.
Which symptoms are typical of HPU?
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Because zinc, vitamin B6 and manganese are involved in hundreds of enzyme processes, HPU often shows up as a broad spectrum of complaints. Common signs include:
Persistent exhaustion, fatigue and low stress tolerance
Gastrointestinal problems and food intolerances (e.g. histamine or gluten sensitivity)
Muscle and joint pain
Poor concentration (“brain fog”) and mood swings
Irregular cycles or hormonal imbalances
How do I prepare for the test?
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To avoid distorting the test result, certain supplements should be paused before collecting the urine sample:
Zinc, vitamin B6 and manganese: stop taking them at least 7 days before the test (if you have been taking them for months, a longer break of up to 4 weeks is advisable).
Drink enough: drink normally the day before (approx. 1.5 litres) so that the urine is not overly diluted.